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Article

Platelet dysfunction associated with the novel Trp29Cys thromboxane A₂ receptor variant.

Journal of thrombosis and haemostasis : JTH - 1 Mar 2013

Mumford A D, Nisar S, Darnige L, Jones M L, Bachelot-Loza C, Gandrille S, Zinzindohoue F, Fischer A-M, Mundell S J, Gaussem P

Abstract excerpt

BACKGROUND: Genetic variations that affect the structure of the thromboxane A2 receptor (TP receptor) provide insights into the function of this key platelet and vascular receptor, but are very rare in unselected populations. OBJECTIVES: To determine the functional consequences of the TP receptor Trp29Cys (W29C) substitution. PATIENTS/METHODS: We performed a detailed phenotypic analysis of an index case (P1) with...

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Identifiers

PMID: 23279270
DOI: 10.1111/jth.12117

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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