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Article

Rare platelet GPCR variants: what can we learn?

British journal of pharmacology - 1 Jul 2015

Nisar S P, Jones M L, Cunningham M R, Mumford A D, Mundell S J

Abstract excerpt

Platelet-expressed GPCRs are critical regulators of platelet function. Pharmacological blockade of these receptors forms a powerful therapeutic tool in the treatment and prevention of arterial thrombosis associated with coronary atherosclerosis and ischaemic stroke. However, anti-thrombotic drug therapy is associated with high inter-patient variability in therapeutic response and adverse bleeding side effects. In...

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Identifiers

PMID: 25231155
DOI: 10.1111/bph.12941
PMCID: PMC4500363

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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