Article
Genome-wide association study of cardiac structure and systolic function in African Americans: the Candidate Gene Association Resource (CARe) study.
Circulation. Cardiovascular genetics - 1 Feb 2013
Fox Ervin R, Musani Solomon K, Barbalic Maja, Lin Honghuang, Yu Bing, Ogunyankin Kofo O, Smith Nicholas L, Kutlar Abdullah, Glazer Nicole L, Post Wendy S, Paltoo Dina N, Dries Daniel L, Farlow Deborah N, Duarte Christine W, Kardia Sharon L, Meyers Kristin J, Sun Yan V, Arnett Donna K, Patki Amit A, Sha Jin, Cui Xiangqui, Samdarshi Tandaw E, Penman Alan D, Bibbins-Domingo Kirsten, Bůžková Petra, Benjamin Emelia J, Bluemke David A, Morrison Alanna C, Heiss Gerardo, Carr J Jeffrey, Tracy Russell P, Mosley Thomas H, Taylor Herman A, Psaty Bruce M, Heckbert Susan R, Cappola Thomas P, Vasan Ramachandran S
Abstract excerpt
BACKGROUND: Using data from 4 community-based cohorts of African Americans, we tested the association between genome-wide markers (single-nucleotide polymorphisms) and cardiac phenotypes in the Candidate-gene Association Resource study. METHODS AND RESULTS: Among 6765 African Americans, we related age, sex, height, and weight-adjusted residuals for 9 cardiac phenotypes (assessed by echocardiogram or magnetic...
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