Article

Genome-wide association study provides new insights into the genetic architecture and pathogenesis of heart failure

2019-07-10

Abstract excerpt

Heart failure (HF) is a leading cause of morbidity and mortality worldwide 1 . A small proportion of HF cases are attributable to monogenic cardiomyopathies and existing genome-wide association studies (GWAS) have yielded only limited insights, leaving the observed heritability of HF largely unexplained 2–4 . We report the largest GWAS meta-analysis of HF to-date, comprising 47,309 cases and 930,014 controls. We...

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Literature Corpus work: f2fd5601-6f2f-590b-8952-bfe58ea2b8ba
DOI: 10.1101/682013

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