Article
Transmission of HIV-1 minority-resistant variants and response to first-line antiretroviral therapy.
AIDS (London, England) - 31 Jul 2008
Peuchant Olivia, Thiébaut Rodolphe, Capdepont Sophie, Lavignolle-Aurillac Valérie, Neau Didier, Morlat Philippe, Dabis François, Fleury Hervé, Masquelier Bernard
Abstract excerpt
BACKGROUND: The transmission of drug-resistant HIV-1 can impair the virological response to antiretroviral therapy. Minority-resistant variants have been detected in acute seroconverters. We investigated the clinical relevance of the detection of majority and minority-resistant variants in an observational study in antiretroviral therapy naive, recently infected patients. METHODS: We included patients infected...
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