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Article

Minority quasispecies of drug-resistant HIV-1 that lead to early therapy failure in treatment-naive and -adherent patients.

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America - 15 Jan 2009

Metzner Karin J, Giulieri Stefano G, Knoepfel Stefanie A, Rauch Pia, Burgisser Philippe, Yerly Sabine, Günthard Huldrych F, Cavassini Matthias

Abstract excerpt

BACKGROUND: Early virological failure of antiretroviral therapy associated with the selection of drug-resistant human immunodeficiency virus type 1 in treatment-naive patients is very critical, because virological failure significantly increases the risk of subsequent failures. Therefore, we evaluated the possible role of minority quasispecies of drug-resistant human immunodeficiency virus type 1, which are...

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Identifiers

PMID: 19086910
DOI: 10.1086/595703

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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