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Article

Common PPARγ variants C161T and Pro12Ala are not associated with inflammatory bowel disease in an Australian cohort.

Journal of gastrointestinal and liver diseases : JGLD - 1 Dec 2012

Hume Georgia E, Fowler Elizabeth V, Griffiths Lyn R, Doecke James D, Radford-Smith Graham L

Abstract excerpt

BACKGROUND AND AIMS: Peroxisome proliferator-activated receptor (PPAR) γ is a transcription factor, highly expressed in colonic epithelial cells, adipose tissue and macrophages, with an important role in the regulation of inflammatory pathways. The common PPARγ variants C161T and Pro12Ala have recently been associated with Ulcerative Colitis (UC) and an extensive UC phenotype respectively, in a Chinese...

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PMID: 23256116

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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