Article
PPARgamma polymorphisms and cancer risk: a meta-analysis involving 32,138 subjects.
Oncology reports - 1 Aug 2010
Xu Wei, Li Yan, Wang Xueli, Chen Bo, Liu Shan, Wang Yan, Zhao Weihong, Wu Jianqing
Abstract excerpt
The peroxisome proliferator-activated receptor gamma (PPARgamma) has been suggested to act as a tumor suppressor gene. Two common variations of PPARgamma, P12A (Pro12Ala, rs1801282) and C161T (His447His, rs3856806), are thought to have an effect on susceptibility to various carcinomas but the results are inconsistent. In this meta-analysis, we assessed published studies of the association between two common...
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