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Article

Distribution of peroxisome proliferator-activated receptor-gamma polymorphisms in Chinese and Dutch patients with inflammatory bowel disease.

Inflammatory bowel diseases - 1 Feb 2010

Shrestha Umid Kumar, Karimi Ouafae, Crusius J Bart A, Zhou Feng, Wang Zhongli, Chen Zhitao, van Bodegraven A A, Xiao Jun, Morré Servaas A, Wang Hongling, Li Jin, Xia Bing

Abstract excerpt

BACKGROUND: As peroxisome proliferator-activated receptor-gamma (PPAR-gamma) is frequently expressed in colon, its genetic polymorphism may play a role in the etiology of inflammatory bowel disease (IBD). The aims of the present study were to determine the distribution of PPAR-gamma polymorphisms Pro12Ala and C161T and to explore the association between the PPAR-gamma genotypes and phenotypes of IBD patients....

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PMID: 19714744
DOI: 10.1002/ibd.21059

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