Article
Polymorphisms in NF-κB, PXR, LXR, PPARγ and risk of inflammatory bowel disease.
World journal of gastroenterology - 14 Jan 2011
Andersen Vibeke, Christensen Jane, Ernst Anja, Jacobsen Bent A, Tjønneland Anne, Krarup Henrik B, Vogel Ulla
Abstract excerpt
AIM: To investigate the contribution of polymorphisms in nuclear receptors to risk of inflammatory bowel disease (IBD). METHODS: Genotypes of nuclear factor (NF)-κB (NFKB1) NFκB -94ins/del (rs28362491); peroxisome proliferator-activated receptor (PPAR)-γ (PPARγ) PPARγ Pro12Ala (rs 1801282) and C1431T (rs 3856806); pregnane X receptor (PXR) (NR1I2) PXR A-24381C (rs1523127), C8055T (2276707), and A7635G (rs...
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