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Article

Peroxisome proliferator-activated receptor γ 2 mutation may cause a subset of ulcerative colitis.

Pediatrics international : official journal of the Japan Pediatric Society - 1 Oct 2010

Aoyagi Yo, Nagata Satoru, Kudo Takahiro, Fujii Toru, Wada Mariko, Chiba Yukihide, Ohtsuka Yoshikazu, Yamashiro Yuichiro, Shimizu Toshiaki, Ohkusa Toshifumi

Abstract excerpt

AIM: Previous studies suggest the homeostasis between acquisition of tolerance to the indigenous microflora and protective immune responses appears to be disrupted in inflammatory bowel disease (IBD). Some experimental studies indicate peroxisome proliferator-activated receptor γ (PPARγ) has been implicated as a regulator of intestinal inflammatory responses. In addition, the toll-like receptor (TLR)-4 can...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 20591056
DOI: 10.1111/j.1442-200X.2010.03195.x

Genes

NOD2
TLR4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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