Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Nuclear pregnane X receptor single nucleotide polymorphism (-25385C/T) is not associated with inflammatory bowel disease in pediatric patients.

Journal of pediatric gastroenterology and nutrition - 1 Jul 2009

Lacher Martin, Kappler Roland, Schroepf Sebastian, Berkholz Stefan, Ballauff Antje, Bufler Philip, Baurecht Hansjoerg, von Schweinitz Dietrich, Koletzko Sibylle

Abstract excerpt

OBJECTIVE: Studies in adults characterized the role of the pregnane X receptor (PXR) in the pathophysiology of inflammatory bowel disease (IBD) with conflicting results; pediatric studies are still lacking. PATIENTS AND METHODS: Genotyping for the -25385C/T polymorphism of the PXR gene in 187 white children with IBD and 185 controls. Determination of colonic PXR expression in selected patients with IBD. RESULTS:...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Child
Share to Child, Preschool

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Infant

Share to Inflammatory Bowel Diseases

Share to Polymerase Chain Reaction

Share to Pregnane X Receptor

Share to Receptors, Steroid

Share to RNA, Messenger

Source

Identifiers

PMID: 19516190
DOI: 10.1097/MPG.0b013e31818de1a8

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 11 closest

Nuclear pregnane X receptor single nucleotide polymorphism (-25385C/T) is not associated with inflammatory bowel disease in pediatric patients.PMID 19516190Read ↗

Investigation of associations between the pregnane-X receptor gene (NR1I2) and Crohn's disease in Canadian children using a gene-wide haplotype-based approach.Semantic proximity Read ↗

The pregnane X receptor locus is associated with susceptibility to inflammatory bowel disease.Semantic proximity Read ↗

Pregnane X Receptor Polymorphisms and Risk of Inflammatory Bowel Disease: A Meta-Analysis.Semantic proximity Read ↗

Role of the PXR gene locus in inflammatory bowel diseases.Semantic proximity Read ↗

Pregnane X receptor (PXR/NR1I2) gene haplotypes modulate susceptibility to inflammatory bowel disease.Semantic proximity Read ↗

Common PPARγ variants C161T and Pro12Ala are not associated with inflammatory bowel disease in an Australian cohort.Semantic proximity Read ↗

Farnesoid X receptor (FXR) activation and FXR genetic variation in inflammatory bowel disease.Semantic proximity Read ↗

Functional P2X7 receptor polymorphisms (His155Tyr, Arg307Gln, Glu496Ala) in patients with Crohn's disease.Semantic proximity Read ↗

The CC chemokine receptor 5 delta32 mutation is not associated with inflammatory bowel disease (IBD) in NE England.Semantic proximity Read ↗

No association between the functional cannabinoid receptor type 2 Q63R variants and inflammatory bowel disease in Turkish subjects.Semantic proximity Read ↗

SNPs in the FOXP3 gene region show no association with Juvenile Idiopathic Arthritis in a UK Caucasian population.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.