Article
Involvement of the mu-opioid receptor gene polymorphism A118G in the efficacy of detoxification of alcohol dependent patients.
Addictive behaviors - 1 Mar 2013
Marini Valeria, Fucile Carmen, Zuccoli Maria Laura, Testino Giovanni, Sumberaz Alessandro, Robbiano Luigi, Martelli Antonietta, Mattioli Francesca
Abstract excerpt
INTRODUCTION: The A118G (rs 1799971) polymorphism in the mu-opioid receptor gene (OPRM1) has been reported to be associated with alcohol addiction. METHODS: In this study 109 patients diagnosed with alcohol dependence in accordance with DMS-IV criteria and 95 healthy subjects were enrolled and everyone has been genotyped. RESULTS: The percentage of alcoholic patients with higher than normal gamma-glutamyl...
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