Article
Association of the OPRM1 variant rs1799971 (A118G) and clinical manifestations in tramadol poisoned patients: a cross-sectional study.
Clinical toxicology (Philadelphia, Pa.) - 1 Jun 2024
Ershad Ali, Shafiee Dolat Abadi Sahel, Ebrahimian Melika, Hadeiy Seyed Kaveh, Zamani Naghmeh, Kolahi Ali-Asghar, Movafagh Abolfazl, Hassanian-Moghaddam Hossein
Abstract excerpt
INTRODUCTION: The opioid receptor mu1 is a protein coding gene that can have different codes for a protein and may have variations (polymorphisms) affecting how opioids work. The aim of this study was to investigate the prevalence of the most common opioid receptor mu1 polymorphism (A118G) and any relationship between this polymorphism and features following tramadol overdose. MATERIALS AND METHODS: This was a...
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