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Article

Epidermal growth factor receptor (EGFR) mutations and expression in squamous cell carcinoma of the esophagus in central Asia.

BMC cancer - 17 Dec 2012

Abedi-Ardekani Behnoush, Dar Nazir Ahmad, Mir Mohammad Muzaffar, Zargar Showkat Ahmad, Lone M Muqbool, Martel-Planche Ghyslaine, Villar Stéphanie, Mounawar Mounia, Saidi Farrokh, Malekzadeh Reza, Hainaut Pierre

Abstract excerpt

BACKGROUND: Esophageal squamous cell carcinoma (ESCC) shows geographic variations in incidence, with high incidences (>50/105 person-years) in central Asia, including North Eastern Iran (Golestan) and Northern India (Kashmir). In contrast to Western countries, smoking does not appear to be a significant risk factor for ESCC in central Asia. In lung adenocarcinoma, activating mutations in the gene encoding...

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Identifiers

PMID: 23244191
DOI: 10.1186/1471-2407-12-602
PMCID: PMC3543241

Genes

EGFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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