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Article

Epidermal growth factor receptor structural alterations in gastric cancer.

BMC cancer - 16 Jan 2008

Moutinho Cátia, Mateus Ana R, Milanezi Fernanda, Carneiro Fátima, Seruca Raquel, Suriano Gianpaolo

Abstract excerpt

BACKGROUND: EGFR overexpression has been described in many human tumours including gastric cancer. In NSCLC patients somatic EGFR mutations, within the kinase domain of the protein, as well as gene amplification were associated with a good clinical response to EGFR inhibitors. In gastric tumours...

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Topics

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Share to Carcinoma
Share to Gene Amplification
Share to Gene Expression Regulation, Enzymologic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to In Situ Hybridization, Fluorescence

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Source

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Identifiers

PMID: 18199332
DOI: 10.1186/1471-2407-8-10
PMCID: PMC2244615

Genes

EGFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18199332-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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