Article
Alterations in epidermal growth factor receptors 1 and 2 in esophageal squamous cell carcinomas.
BMC cancer - 4 Dec 2012
Gonzaga Isabela Martins, Soares-Lima Sheila Coelho, de Santos Paulo Thiago Souza, Blanco Tania Cristina Moita, de Reis Bruno Souza Bianchi, Quintella Danielle Carvalho, de Oliveira Ivanir Martins, de Faria Paulo Antonio Silvestre, Kruel Cleber Dario Pinto, Andreollo Nelson Adami, de Simão Tatiana Almeida, Pinto Luis Felipe Ribeiro
Abstract excerpt
BACKGROUND: Esophageal squamous cell carcinoma (ESCC) shows a 5-year survival rate below 10%, demonstrating the urgency in improving its treatment. Alterations in epidermal growth factor receptors are closely related to malignancy transformation in a number of tumors and recent successful targeted therapies have been directed to these molecules. Therefore, in this study, we analyzed the expression of EGFR and...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.