Article
Worldwide Frequency of Commonly Detected EGFR Mutations.
Archives of pathology & laboratory medicine - 1 Feb 2018
Graham Rondell P, Treece Amanda L, Lindeman Neal I, Vasalos Patricia, Shan Mu, Jennings Lawrence J, Rimm David L
Abstract excerpt
CONTEXT: - Recurrent epidermal growth factor receptor ( EGFR) mutations are seen in a subset of pulmonary adenocarcinomas. These mutations are targeted by EGFR inhibitors and are a biomarker for response to EGFR inhibitor therapies. Initial data have indicated an increased frequency of activating EGFR mutations in nonsmoking Asian females. However, there are very few studies of global scope that address the...
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