Article
Identification of EGFR and KRAS mutations in Chinese patients with esophageal squamous cell carcinoma.
Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus - 1 Jul 2011
Liu Q-W, Fu J-H, Luo K-J, Yang H-X, Wang J-Y, Hu Y, Yang H, Bella E
Abstract excerpt
The prognosis of esophageal squamous cell carcinoma (ESCC) is poor. It is urgent to improve this situation. Epidermal growth factor receptor (EGFR)-targeted therapy possesses a promising clinical efficacy. Mutations of EGFR and V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog (KRAS) have been identified in esophageal carcinoma, but corresponding Chinese data are limited. So we investigated the mutation status...
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