Article
Epidermal growth factor receptor gene mutations in patients with lung adenocarcinoma differ by frequency and type between Uighur and Han ethnic groups in Xinjiang Autonomous Region.
BMC genetics - 28 Feb 2015
Li Xiaoqin, Wang Xiuli, Zhu Hongge, Liu Chunling, Zhou Xin, Zhao Bing, Duan Huijie, Yang Jia, Gu Guomin, Zhan Yiyi, Yuan Jing, Abuduwaili Kahaer, Qionglu Su
Abstract excerpt
BACKGROUND: This study was designed to investigate epidermal growth factor receptor (EGFR) mutation types affecting lung cancer treatment in patients in Xinjiang, China. We detected and analyzed differences in the EGFR mutation points of Uighur and Han patients with lung adenocarcinoma. We examined 181 specimens of lung adenocarcinoma tissue embedded with paraffin (76 Uighur and 105 Han patients) for mutations in...
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