Article
Correlation of epidermal growth factor receptor mutation, immunohistochemistry, and fluorescence in situ hybridization in esophageal squamous cell carcinoma.
Journal of the Medical Association of Thailand = Chotmaihet thangphaet - 1 Sept 2009
Sunpaweravong Patrapim, Suwiwat Supaporn, Sunpaweravong Somkiat, Puttawibul Puttisak, Mitarnun Winyou
Abstract excerpt
BACKGROUND: The epidermal growth factor receptor (EGFR) has become a promising target for novel anticancer therapy Evaluation of its biological profiles including gene mutation, amplification, and protein expression in esophageal squamous cell carcinoma (ESCC) is essential to establish the EGFR molecular feature(s) suitable to select patients in anti-EGFR therapy. MATERIAL AND METHOD: The subjects' specimens of...
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