Article
Validating GWAS-Identified Risk Loci for Alzheimer's Disease in Han Chinese Populations.
Molecular neurobiology - 1 Jan 2016
Wang Hui-Zhen, Bi Rui, Hu Qiu-Xiang, Xiang Qun, Zhang Chen, Zhang Deng-Feng, Zhang Wen, Ma Xiaohong, Guo Wanjun, Deng Wei, Zhao Liansheng, Ni Peiyan, Li Mingli, Fang Yiru, Li Tao, Yao Yong-Gang
Abstract excerpt
In recent years, genome-wide association studies (GWASs) have identified many novel susceptible genes/loci for Alzheimer's disease (AD). However, most of these studies were conducted in European and populations of European origin, and limited studies have been performed in Han Chinese. In this study, we genotyped 14 single-nucleotide polymorphisms (SNPs) in eight GWAS-reported AD risk genes in 1509 individuals...
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