Article
Polygenic Analysis of Late-Onset Alzheimer's Disease from Mainland China.
PloS one - 1 Jan 2015
Jiao Bin, Liu Xiaoyan, Zhou Lin, Wang Maggie Haitian, Zhou Yafang, Xiao Tingting, Zhang Weiwei, Sun Rui, Waye Mary Miu Yee, Tang Beisha, Shen Lu
Abstract excerpt
Recently, a number of single nucleotide polymorphisms (SNPs) were identified to be associated with late-onset Alzheimer disease (LOAD) through genome-wide association study data. Identification of SNP-SNP interaction played an important role in better understanding genetic basis of LOAD. In this study, fifty-eight SNPs were screened in a cohort of 229 LOAD cases and 318 controls from mainland China, and their...
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