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Article

Interactive association of five candidate polymorphisms in Apelin/APJ pathway with coronary artery disease among Chinese hypertensive patients.

PloS one - 1 Jan 2012

Jin Wei, Su Xiuxiu, Xu Min, Liu Yan, Shi Jingyi, Lu Lin, Niu Wenquan

Abstract excerpt

BACKGROUND: Via sequencing the genes of apelin/angiotensin receptor-like 1 (apelin/APJ) pathway, we have recently identified and validated four common polymorphisms (rs3761581, rs56204867, rs7119375, and rs10501367) implicated in the development of hypertension. Extending these findings, we, in Chinese hypertensive patients, sought to investigate the association of these four polymorphisms and one additional...

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Share to Coronary Artery Disease
Share to Epistasis, Genetic
Share to Genetic Loci
Share to Genome, Human
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Share to Intercellular Signaling Peptides and Proteins
Share to Multifactor Dimensionality Reduction
Share to Receptors, G-Protein-Coupled

Source

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PMID: 23226564
DOI: 10.1371/journal.pone.0051123
PMCID: PMC3513301

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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