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Article

Associations of common variants at APLN and hypertension in Chinese subjects with and without diabetes.

Experimental diabetes research - 1 Jan 2012

Zhang Rong, Lu Jingyi, Hu Cheng, Wang Congrong, Yu Weihui, Jiang Feng, Tang Shanshan, Bao Yuqian, Xiang Kunsan, Jia Weiping

Abstract excerpt

BACKGROUND: Apelin, the endogenous ligand for the APJ receptor, has a potent hypotensive effect via a nitric oxide-dependent mechanism in vivo. The aim of the study was to investigate the association between the common variants of apelin gene (APLN) and hypertension, which was reported recently in a Chinese Han population with and without diabetes. METHODS: Three single nucleotide polymorphisms (SNPs) on APLN...

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Source

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Identifiers

PMID: 23316219
DOI: 10.1155/2012/917496
PMCID: PMC3534217

Genes

APLN

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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