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Article

Biochemical and genetic role of apelin in essential hypertension and acute coronary syndrome.

International journal of cardiology - 15 Nov 2016

Gupta Mohit D, Girish M P, Shah Dhaval, Rain Manjari, Mehta Vimal, Tyagi Sanjay, Trehan Vijay, Pasha Qadar

Abstract excerpt

BACKGROUND: Apelin-APJ pathway has emerged as a potent regulator of blood pressure (BP) and blood flow in vasculature and heart. Variants in apelin gene may affect the vascular tone in peripheral circulation or heart, thereby predisposing to cardiovascular diseases. The aim of our study was to investigate the association of two apelin gene polymorphisms rs3761581 and rs2235312, and apelin levels in patients with...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 27543713
DOI: 10.1016/j.ijcard.2016.07.242

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