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Article

Reduced plasma APJ levels and APLNR G212A polymorphism in Syrian patients with coronary artery disease.

Current medical research and opinion - 1 Mar 2026

Abd-Alkareem Maisaa Hassan, Mohammed Shibli Hussam Eddin, Alquobaili Faizeh Ali

Abstract excerpt

BACKGROUND: Coronary artery disease (CAD) remains a leading global cause of mortality. The apelin/apelin receptor (APJ) system has emerged as a novel pathway implicated in cardiovascular regulation and disease progression. This pioneering case-control study, the first conducted in a Syrian population, investigated the association of the apelin receptor G212A polymorphism and plasma APJ levels with CAD...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Intercellular Signaling Peptides and Proteins

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Share to Receptors, G-Protein-Coupled

Source

Identifiers

PMID: 42207182
DOI: 10.1080/03007995.2026.2668774

Genes

CAD
APLNR

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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