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Article

APJ polymorphisms in coronary artery disease patients with and without hypertension.

Molecular medicine reports - 1 Feb 2012

Falcone Colomba, Bozzini Sara, Schirinzi Sandra, Buzzi Maria Paola, Boiocchi Chiara, Totaro Rossana, Bondesan Marialisa, Pelissero Gabriele

Abstract excerpt

Apelin is an endogenous peptide that increases cardiac inotropism through its APJ receptor. Certain findings indicate that the apelinergic system may have a pathophysiological role in cardiovascular disease and there is evidence showing the role of the apelinergic system in blood pressure regulation in vitro and in animal models. The role of the apelin-APJ system in cardiovascular physiology and its interaction...

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Identifiers

PMID: 22109355
DOI: 10.3892/mmr.2011.685

Genes

CAD

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