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Article

Association of polymorphisms of leptin, leptin receptor and apelin receptor genes with susceptibility to coronary artery disease and hypertension.

Life sciences - 15 Aug 2018

Nowzari Zohreh, Masoumi Mohammad, Nazari-Robati Mahdieh, Akbari Hamed, Shahrokhi Nader, Asadikaram Gholamreza

Abstract excerpt

AIMS: Apelin and leptin are factors which have a potential physiological and pathological role in cardiovascular homoeostasis. Apelin receptor (APLNR), leptin receptor (LEPR) and leptin variants may affect the vascular tone in heart or peripheral circulation, thereby predisposing patients to hypertension and coronary artery disease (CAD). The aim of the present study was to evaluate four single nucleotide...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 29883719
DOI: 10.1016/j.lfs.2018.06.007

Genes

CAD
APLNR
LEPR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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