Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A promoter polymorphism in APJ gene is significantly associated with blood pressure changes and hypertension risk in Chinese women.

Oncotarget - 27 Dec 2016

Li Guofeng, Sun Xingyuan, Zhao Dalong, He Lan, Zheng Lihong, Xue Jing, Wang Bin, Pan Hongming

Abstract excerpt

The aim of this study was to interrogate the gender-specific association of 5 well-defined polymorphisms in apelin/APJ system with both blood pressure changes and hypertension risk in a northeastern Chinese population. This is a population-based case-control study, including 650 hypertensive patients and 645 normotensive controls. Data were analyzed by STATA and Haplo.Stats. The genotype distributions of 5 study...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged
Share to Asian People

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Blood Pressure

Share to Case-Control Studies

Share to Genetic Predisposition to Disease

Share to Hypertension

Share to Polymorphism, Single Nucleotide

Share to Promoter Regions, Genetic

Source

Open in PubMed Open full text

Identifiers

PMID: 27863393
DOI: 10.18632/oncotarget.13370
PMCID: PMC5349911

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A promoter polymorphism in APJ gene is significantly associated with blood pressure changes and hypertension risk in Chinese women.PMID 27863393Read ↗

Associations between gene polymorphisms of the apelin-APJ system and the risk of hypertension.Semantic proximity Read ↗

The APLNR gene polymorphism rs7119375 is associated with an increased risk of development of essential hypertension in the Chinese population: A meta-analysis.Semantic proximity Read ↗

Biochemical and genetic role of apelin in essential hypertension and acute coronary syndrome.Semantic proximity Read ↗

Interactive association of five candidate polymorphisms in Apelin/APJ pathway with coronary artery disease among Chinese hypertensive patients.Semantic proximity Read ↗

The relationship between three X-linked genes and the risk for hypertension among northeastern Han Chinese.Semantic proximity Read ↗

Associations of common variants at APLN and hypertension in Chinese subjects with and without diabetes.Semantic proximity Read ↗

Association of genetic variants in the apelin-APJ system and ACE2 with blood pressure responses to potassium supplementation: the GenSalt study.Semantic proximity Read ↗

Validation of genetic association in apelin-AGTRL1 system with hypertension in a larger Han Chinese population.Semantic proximity Read ↗

ATP2B1 gene polymorphisms rs2681472 and rs17249754 are associated with susceptibility to hypertension and blood pressure levels: A systematic review and meta-analysis.Semantic proximity Read ↗

Association between single-nucleotide polymorphisms in six hypertensive candidate genes and hypertension among northern Han Chinese individuals.Semantic proximity Read ↗

MicroRNA-765 influences arterial stiffness through modulating apelin expression.Semantic proximity Read ↗

Association of genetic variants in Leptin, leptin receptor and adiponectin with hypertension risk and circulating Leptin/Adiponectin changes.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.