Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Decreased levels of circulating IL17-producing CD161+CCR6+ T cells are associated with graft-versus-host disease after allogeneic stem cell transplantation.

PloS one - 1 Jan 2012

van der Waart Anniek B, van der Velden Walter J F M, van Halteren Astrid G S, Leenders Marij J L G, Feuth Ton, Blijlevens Nicole M A, van der Voort Robbert, Dolstra Harry

Abstract excerpt

The C-type lectin-like receptor CD161 is a well-established marker for human IL17-producing T cells, which have been implicated to contribute to the development of graft-versus-host disease (GVHD) after allogeneic stem cell transplantation (allo-SCT). In this study, we analyzed CD161(+) T cell re...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to CD4-Positive T-Lymphocytes
Share to CD8-Positive T-Lymphocytes

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cyclosporine

Share to Graft vs Host Disease

Share to Immunologic Memory

Share to Interleukin-17

Share to Stem Cell Transplantation

Share to Transplantation, Homologous

Source

Open in PubMed Open full text

Identifiers

PMID: 23226545
DOI: 10.1371/journal.pone.0050896
PMCID: PMC3514180

Genes

CCR6
CCL20
SCT
ABCB1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23226545-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Decreased levels of circulating IL17-producing CD161+CCR6+ T cells are associated with graft-versus-host disease after allogeneic stem cell transplantation.PMID 23226545Read ↗

CD161 defines a transcriptional and functional phenotype across distinct human T cell lineages.Semantic proximity Read ↗

The quest continues: Human CD4 <sup>+</sup> CD16 <sup>+</sup> CD56 <sup>+</sup> ‘exTreg’ resemble NKT cells insteadSemantic proximity Read ↗

Circulating and gut-resident human Th17 cells express CD161 and promote intestinal inflammation.Semantic proximity Read ↗

Increased frequency of CD4+ cells expressing CD161 in cancer patients.Semantic proximity Read ↗

Multifunctional human CD56 low CD16 low natural killer cells are the prominent subset in bone marrow of both healthy pediatric donors and leukemic patients.Semantic proximity Read ↗

Increased plasticity of non-classic Th1 cells toward the Th17 phenotypeSemantic proximity Read ↗

Impact of Aging on the Frequency, Phenotype, and Function of CD161-Expressing T Cells.Semantic proximity Read ↗

Dynamic regulation of effector IFN-γ-producing and IL-17-producing T cell subsets in the development of acute graft-versus-host disease.Semantic proximity Read ↗

Immature and activated phenotype of blood NK cells is associated with acute rejection in adult liver transplant.Semantic proximity Read ↗

An unusual CD56(bright) CD16(low) NK cell subset dominates the early posttransplant period following HLA-matched hematopoietic stem cell transplantation.Semantic proximity Read ↗

A shift towards pro-inflammatory CD16+ monocyte subsets with preserved cytokine production potential after kidney transplantation.Semantic proximity Read ↗

PLZF regulates CCR6 and is critical for the acquisition and maintenance of the Th17 phenotype in human cells.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.