Article
A shift towards pro-inflammatory CD16+ monocyte subsets with preserved cytokine production potential after kidney transplantation.
PloS one - 1 Jan 2013
Vereyken Elly J F, Kraaij Marina D, Baan Carla C, Rezaee Farhad, Weimar Willem, Wood Kathryn J, Leenen Pieter J M, Rowshani Ajda T
Abstract excerpt
BACKGROUND: The presence of monocyte-macrophage lineage cells in rejecting kidney transplants is associated with worse graft outcome. At present, it is still unclear how the monocyte-macrophage related responses develop after transplantation. Here, we studied the dynamics, phenotypic and functional characteristics of circulating monocytes during the first 6 months after transplantation and aimed to establish the...
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