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Article

A Comparative Analysis of Genetic and Epigenetic Factors in METH Addiction: A Focus on SLC (SLC6A4) and COMT Genes.

Frontiers in bioscience (Landmark edition) - 31 Jul 2025

Hussain Haider K, Tejada Yolanda Loarce, Barbaro Anna

Abstract excerpt

BACKGROUND: Methamphetamine (METH) addiction is a global concern due to its severe impact on public health, including heightened aggression and neurotoxic effects. Genetic and epigenetic factors, particularly involving the SLC6A4 and COMT genes, are implicated in individual vulnerability to METH addiction. Thus, understanding the molecular mechanisms involved is crucial for developing targeted prevention and...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 40765345
DOI: 10.31083/FBL43887

Genes

COMT
SLC6A4

Variants

Provenance

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