Article
GWAS-uncovered SNPs in PLCE1 and RFT2 genes are not implicated in Dutch esophageal adenocarcinoma and squamous cell carcinoma etiology.
European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP) - 1 Sept 2013
Dura Polat, Bregitha Caro V V, te Morsche Rene H M, Roelofs Hennie M J, Kristinsson Jon O, Wobbes Theo, Witteman Ben J M, Tan Adriaan C I T L, Drenth Joost P H, Peters Wilbert H M
Abstract excerpt
Susceptibility to esophageal carcinoma (EC) is influenced by the interaction between genetic and environmental factors. To clarify the etiology of EC, several genome-wide association studies have identified single nucleotide polymorphisms (SNPs) in PCLE1 and RFT2 genes as esophageal squamous cell carcinoma (ESCC) susceptibility loci in Asian populations. This study aimed to determine whether these SNPs also...
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