Article
Replication study of PLCE1 and C20orf54 polymorphism and risk of esophageal cancer in a Chinese population.
Molecular biology reports - 1 Sept 2012
Gu Haiyong, Ding Guowen, Zhang Wenbo, Liu Chao, Chen Yijang, Chen Suocheng, Jiang Pengcheng
Abstract excerpt
Esophageal cancer is one of the most aggressive cancers in the world. Recent large-scale genome-wide association studies (GWAS) reported that functional genetic variations in the phospholipase C epsilon gene (PLCE1) were strongly associated with risk of esophageal squamous cell carcinoma (ESCC) and gastric cardia adenocarcinoma (GCA) in Chinese population. For C20orf54 rs13042395 genotype and risk of esophageal...
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