Novel functional variants locus in PLCE1 and susceptibility to esophageal squamous cell carcinoma: based on published genome-wide association studies in a central Chinese population.

doi:10.1016/j.canep.2013.04.009

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Novel functional variants locus in PLCE1 and susceptibility to esophageal squamous cell carcinoma: based on published genome-wide association studies in a central Chinese population.

Cancer epidemiology - 1 Oct 2013

Duan Fujiao, Xie Wei, Cui Lihong, Wang Peng, Song Chunhua, Qu Honghong, Wang Kaijuan, Zhang Jianying, Dai Liping

Abstract excerpt

A novel functional single nucleotide polymorphism (SNP) rs2274223 located in the phospholipase C epsilon 1 (PLCE1) gene was found to be associated with the risk of esophageal squamous cell carcinoma (ESCC) by three large-scale genome-wide association studies (GWAS) in Chinese populations. In the present study, we validated this finding and also explored the risk of ESCC associated with other two unreported...

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Identifiers

PMID: 23688607
DOI: 10.1016/j.canep.2013.04.009

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PLCE1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

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