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Article

Role of novel and GWAS originated PLCE1 genetic variants in susceptibility and prognosis of esophageal cancer patients in northern Indian population.

Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Nov 2014

Umar Meenakshi, Upadhyay Rohit, Kumar Shaleen, Ghoshal Uday Chand, Mittal Balraj

Abstract excerpt

Recent genome-wide association studies (GWAS) have identified variants in phospholipase C epsilon1 (PLCE1) as novel susceptibility markers for esophageal squamous cell carcinoma (ESCC) in Chinese population. Although few studies have replicated this findings in other populations, but results are contradictory. So, we aimed to replicate association of two previously reported non-synonymous polymorphisms...

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Topics

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Share to Carcinoma, Squamous Cell
Share to Esophageal Neoplasms

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 25139097
DOI: 10.1007/s13277-014-2458-z

Genes

PLCE1

Variants

rs2274223
rs2274223

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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