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Article

Novel functional variants locus in PLCE1 and susceptibility to digestive tract cancer in the Chinese population: a meta-analysis.

The International journal of biological markers - 9 Dec 2014

Duan Fujiao, Song Chunhua, Dai Liping, Cui Shuli, Zhang Xiaoqin, Zhao Xia

Abstract excerpt

Three large-scale genome-wide association studies (GWAS) have identified a shared susceptibility variation phospholipase C epsilon 1 (PLCE1) rs2274223 for esophageal squamous cell carcinoma (ESCC) and/or gastric cardia adenocarcinomas (GCA) in the Chinese population. However, the association between PLCE1 rs2274223 A>G and the risk of digestive tract cancer (DTC) has been inconsistent. We therefore carried out a...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 24874112
DOI: 10.5301/jbm.5000090

Genes

PLCE1
GCA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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Novel functional variants locus in PLCE1 and susceptibility to digestive tract cancer in the Chinese population: a meta-analysis.PMID 24874112Read ↗

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Novel functional variants locus in PLCE1 and susceptibility to esophageal squamous cell carcinoma: based on published genome-wide association studies in a central Chinese population.Semantic proximity Read ↗

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Esophageal squamous cell carcinoma and gastric cardia adenocarcinoma shared susceptibility locus in PLCE1: a meta-analysis.Semantic proximity Read ↗

PLCE1 rs2274223 polymorphism and susceptibility to esophageal cancer: a meta-analysis.Semantic proximity Read ↗

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