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Article

Human leukocyte antigen-G allele polymorphisms have evolved following three different evolutionary lineages based on intron sequences.

Human immunology - 1 Nov 2010

Cervera Isabel, Herraiz Miguel Angel, Peñaloza Jorge, Barbolla Maria Luz, Jurado Maria Luisa, Macedo Jacqueline, Vidart José Antonio, Martinez-Laso Jorge

Abstract excerpt

Human leukocyte antigen (HLA)-G alleles follow a different pattern of polymorphism generation from those of the HLA classical I alleles. These polymorphisms have been defined as a result of random permitted point mutations in exons. However, this polymorphism maintenance could have an evolutionary specific pathways based on noncoding regions as introns, 14-bp deletion/insertion (exon 8), or promoter regions....

Read the complete abstract on PubMed

Topics

Alleles
Base Sequence
Evolution, Molecular
HLA Antigens
HLA-G Antigens
Histocompatibility Antigens Class I

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Humans

Inteins

Molecular Sequence Data

Phylogeny

Polymorphism, Genetic

Source

Identifiers

PMID: 20650296
DOI: 10.1016/j.humimm.2010.07.003

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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