Article
The emerging diversity of transpososome architectures.
Quarterly reviews of biophysics - 1 Nov 2012
Dyda Fred, Chandler Michael, Hickman Alison Burgess
Abstract excerpt
DNA transposases are enzymes that catalyze the movement of discrete pieces of DNA from one location in the genome to another. Transposition occurs through a series of controlled DNA strand cleavage and subsequent integration reactions that are carried out by nucleoprotein complexes known as transpososomes. Transpososomes are dynamic assemblies which must undergo conformational changes that control DNA breaks and...
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