Article
Unexpected structural diversity in DNA recombination: the restriction endonuclease connection.
Molecular cell - 1 Jun 2000
Hickman A B, Li Y, Mathew S V, May E W, Craig N L, Dyda F
Abstract excerpt
Transposition requires a coordinated series of DNA breakage and joining reactions. The Tn7 transposase contains two proteins: TnsA, which carries out DNA breakage at the 5' ends of the transposon, and TnsB, which carries out breakage and joining at the 3' ends of the transposon. TnsB is a member of the retroviral integrase superfamily whose hallmark is a conserved DDE motif. We report here the structure of TnsA...
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