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Article

Increased lipolysis and altered lipid homeostasis protect γ-synuclein-null mutant mice from diet-induced obesity.

Proceedings of the National Academy of Sciences of the United States of America - 18 Dec 2012

Millership Steven, Ninkina Natalia, Guschina Irina A, Norton Jessica, Brambilla Riccardo, Brambilla Ricardo, Oort Pieter J, Adams Sean H, Dennis Rowena J, Voshol Peter J, Rochford Justin J, Buchman Vladimir L

Abstract excerpt

Synucleins are a family of homologous proteins principally known for their involvement in neurodegeneration. γ-Synuclein is highly expressed in human white adipose tissue and increased in obesity. Here we show that γ-synuclein is nutritionally regulated in white adipose tissue whereas its loss pa...

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Identifiers

PMID: 23213245
DOI: 10.1073/pnas.1210022110
PMCID: PMC3529034

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23213245-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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