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Article

Genetic and dietary regulation of lipid droplet expansion in Caenorhabditis elegans.

Proceedings of the National Academy of Sciences of the United States of America - 9 Mar 2010

Zhang Shaobing O, Box Andrew C, Xu Ningyi, Le Men Johan, Yu Jingyi, Guo Fengli, Trimble Rhonda, Mak Ho Yi

Abstract excerpt

Dietary fat accumulates in lipid droplets or endolysosomal compartments that undergo selective expansion under normal or pathophysiological conditions. We find that genetic defects in a peroxisomal beta-oxidation pathway cause size expansion in lipid droplets that are distinct from the lysosome-r...

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Identifiers

PMID: 20176933
DOI: 10.1073/pnas.0912308107
PMCID: PMC2842062

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20176933-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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