Article
Decreased medial temporal lobe activation in BDNF (66)Met allele carriers during memory encoding.
Neuropsychologia - 1 Oct 2013
Kauppi Karolina, Nilsson Lars-Göran, Adolfsson Rolf, Lundquist Anders, Eriksson Elias, Nyberg Lars
Abstract excerpt
The Met allele of the Brain-derived neurotrophic factor (BDNF) Val(66)Met polymorphism has been associated with impaired activity-dependent secretion of BDNF protein and decreased memory performance. Results from imaging studies relating Val(66)Met to brain activation during memory processing have been inconsistent, with reports of both increased and decreased activation in the Medial Temporal Lobe (MTL) in Met...
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