Article
BDNF Val66Met polymorphism significantly affects d' in verbal recognition memory at short and long delays.
Biological psychology - 1 Jan 2008
Goldberg Terry E, Iudicello Jennifer, Russo Christine, Elvevåg Brita, Straub Richard, Egan Michael F, Weinberger Daniel R
Abstract excerpt
A functional polymorphism at the val66met locus in the BDNF gene has significant effects on the pro-form of the protein in intracellular trafficking and activity-dependent, but not constitutive, secretion. These differences are thought to underlie several findings in humans related to this polymorphism, including markers of neuronal viability, BOLD activation in medial temporal lobe regions, and some aspects of...
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