Article
Functional magnetic resonance imaging of BDNF val66met polymorphism in unmedicated subjects at high genetic risk of schizophrenia performing a verbal memory task.
Psychiatry research - 30 Sept 2010
Baig Benjamin J, Whalley Heather C, Hall Jeremy, McIntosh Andrew M, Job Dominic E, Cunningham-Owens David G, Johnstone Eve C, Lawrie Stephen M
Abstract excerpt
Multiple strands of evidence suggest a role for Brain Derived Neurotrophic Factor (BDNF) in the pathophysiology of schizophrenia. It is not yet clear, however, how BDNF may contribute to altered brain function seen in the disorder, or in those at high genetic risk. The current study examines functional imaging correlates of the BDNF val66met polymorphism in a population at high genetic risk of schizophrenia....
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