Article
Brain-derived neurotrophic factor val66met polymorphism and hippocampal activation during episodic encoding and retrieval tasks.
Hippocampus - 1 Sept 2011
Dennis Nancy A, Cabeza Roberto, Need Anna C, Waters-Metenier Sheena, Goldstein David B, LaBar Kevin S
Abstract excerpt
Brain-derived neurotrophic factor (BDNF) is a neurotrophin which has been shown to regulate cell survival and proliferation, as well as synaptic growth and hippocampal long-term potentiation. A naturally occurring single nucleotide polymorphism in the human BDNF gene (val66met) has been associated with altered intercellular trafficking and regulated secretion of BDNF in met compared to val carriers. Additionally,...
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