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Brain-derived neurotrophic factor val66met polymorphism and hippocampal activation during episodic encoding and retrieval tasks.

Hippocampus - 1 Sept 2011

Dennis Nancy A, Cabeza Roberto, Need Anna C, Waters-Metenier Sheena, Goldstein David B, LaBar Kevin S

Abstract excerpt

Brain-derived neurotrophic factor (BDNF) is a neurotrophin which has been shown to regulate cell survival and proliferation, as well as synaptic growth and hippocampal long-term potentiation. A naturally occurring single nucleotide polymorphism in the human BDNF gene (val66met) has been associated with altered intercellular trafficking and regulated secretion of BDNF in met compared to val carriers. Additionally,...

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Brain-Derived Neurotrophic Factor
Brain Mapping
Hippocampus
Memory, Episodic
Memory, Short-Term

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PMID: 20865733
DOI: 10.1002/hipo.20809
PMCID: PMC3010486

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BDNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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