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Article

Effect of BDNF val(66)met polymorphism on declarative memory and its neural substrate: a meta-analysis.

Neuroscience and biobehavioral reviews - 1 Oct 2012

Kambeitz Joseph P, Bhattacharyya Sagnik, Kambeitz-Ilankovic Lana M, Valli Isabel, Collier David A, McGuire Philip

Abstract excerpt

Brain derived neurotrophic factor (BDNF) is a critical component of the molecular mechanism of memory formation. Variation in the BDNF gene, particularly the rs6265 (val(66)met) single nucleotide polymorphism (SNP), has been linked to variability in human memory performance and to both the structure and physiological response of the hippocampus, which plays a central role in memory processing. However, these...

Topics

Alleles
Brain-Derived Neurotrophic Factor
Genotype
Hippocampus
Humans
Memory
Neuropsychological Tests
Polymorphism, Single Nucleotide

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 22813992
DOI: 10.1016/j.neubiorev.2012.07.002

Genes

BDNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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