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Article

The brain-derived neurotrophic factor Val66Met polymorphism affects memory formation and retrieval of biologically salient stimuli.

NeuroImage - 15 Apr 2010

van Wingen Guido, Rijpkema Mark, Franke Barbara, van Eijndhoven Philip, Tendolkar Indira, Verkes Robbert Jan, Buitelaar Jan, Fernández Guillén

Abstract excerpt

Brain-derived neurotrophic factor (BDNF) is involved in memory and the pathophysiology of various neuropsychiatric disorders. A single nucleotide polymorphism in the human BDNF gene (Val66Met) affects memory, and influences Alzheimer's disease and depression vulnerability in a sex-specific manner. Recent animal studies suggest that BDNF mediates memory for emotional experiences in the amygdala, but it is...

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Brain-Derived Neurotrophic Factor
Brain Mapping
Face
Memory
Pattern Recognition, Visual

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Photic Stimulation

Recognition, Psychology

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PMID: 20097294
DOI: 10.1016/j.neuroimage.2010.01.058

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BDNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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The brain-derived neurotrophic factor Val66Met polymorphism affects memory formation and retrieval of biologically salient stimuli.PMID 20097294Read ↗

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Brain-derived neurotrophic factor val66met polymorphism and hippocampal activation during episodic encoding and retrieval tasks.Semantic proximity Read ↗

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Fine-mapping of the brain-derived neurotrophic factor (BDNF) gene supports an association of the Val66Met polymorphism with episodic memory.Semantic proximity Read ↗

Decreased medial temporal lobe activation in BDNF (66)Met allele carriers during memory encoding.Semantic proximity Read ↗

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