Article
Isolation of highly persistent mutants of Salmonella enterica serovar typhimurium reveals a new toxin-antitoxin module.
Journal of bacteriology - 1 Feb 2013
Slattery Andrew, Victorsen Alec H, Brown April, Hillman Kai, Phillips Gregory J
Abstract excerpt
Bacterial persistence is characterized by the ability of a subpopulation within bacterial cultures to survive exposure to antibiotics and other lethal treatments. The surviving persisters are not the result of genetic changes but represent epigenetic variants that are in a physiological state where growth is inhibited. Since characterization of persisters has been performed mainly in Escherichia coli K-12, we...
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